2019-08-08

Pris: 1769 kr. Häftad, 2014. Skickas inom 10-15 vardagar. Köp Biosimulation in Biomedical Research, Health Care and Drug Development av Erik Mosekilde, Olga Sosnovtseva, Amin Rostami …

Journal of Pharmaceutical and Biomedical Analysis 2020, 178 , 112901. Professor Amin Rostami‐Hodjegan, PharmD, PhD, FCP, Centre for Applied Pharmaceutical Research, Manchester Pharmacy School, University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK. E‐mail: amin.rostami@manchester.ac.uk. Search for more papers by this author Editorial Board Bazigha Abdul-Rasool, Dubai Pharmacy College, Dubai, U.A.E Khosrow Adeli, The Hospital for Sick Children, Canada Shahin Akhondzadeh, Tehran University of Medical Sciences, Iran Massoud Amanlou, Tehran University of Medical Sciences, Iran Gholameza Amin, Tehran University of Medical Sciences, Iran Fatemeh Atyabi, Tehran University of Medical Sciences, Iran Mahdi Balali-Mood Certara will participate in 28 sessions at the conference in addition to helping support the PAGE Student Sponsorship and PAGE Football Championship. PRINCETON, NJ – May 29, 2018 – Certara ®, the global leader in model-informed drug development, regulatory science, health economic outcomes research, market access and real-world evidence services, today announced its participation in 28 Abstract: In vivo enzyme levels are governed by the rates of de novo enzyme synthesis and degradation. A current lack of consensus on values of the in vivo turnover half-lives of human cytochrome P450 (CYP) enzymes places a significant limitation on the accurate prediction of changes in drug concentration-time profiles associated with interactions involving enzyme induction and mechanism (time [1] Brahim Achour, Matthew R. Russel, Jill Barber, and Amin Rostami-Hodjegan, Simultaneous Quantification of the Abundance of Several Cytochrome P450 and Uridine 59-Diphospho-Glucuronosyltransferase Enzymes in Human Liver Microsomes Using Multiplexed Targeted Proteomics, Drug Metab Dispos 42:500–510 (2014) Amin Rostami-Hodjegan , Geoffrey T Tucker and Simcyp Ltd, The Blades Enterprise Centre, John Street, Sheffield S2 4SU, UK. a.rostami@sheffield.ac.uk. Alice Ban Ke,1 Amin Rostami-Hodjegan,2,3 Ping Zhao,4 and Jashvant D. Unadkat5.

Amin rostami-hodjegan

J Clin Psychopharmacol 2004; 24: 70 –8. 演者： Amin Rostami-Hodjegan （Centre for Applied Pharmacokinetic Research, University of Manchester, UK ／Certara, Princeton, New Jersey, USA.）トランスポーターDISシンポジウム（シンポジウム12） 12月12日（木）13:45～15:45 D会場（大会議室101） Amin Rostami-Hodjegan,∇, Imran Shah, Martin F. Wilks,§ and Shana J. Sturla*,¶ †Center for Alternatives to Animal Testing (CAAT), Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, United States ‡University of Konstanz, CAAT-Europe, 78457 Konstanz, Germany Amin Rostami-Hodjegan, PharmD, PhD. Dr. Rostami-Hodjegan is a Professor of Systems Pharmacology at the Centre for Applied Pharmacokinetic Research (CAPKR) in the School of Pharmacy and Pharmaceutical Sciences at the University of Manchester. Model-informed precision dosing (MIPD) has become synonymous with modern approaches for individualizing drug therapy, in which the characteristics of each patient are considered as opposed to applying a one-size-fits-all alternative. This review provides a brief account of the current knowledge, pra … In vivo enzyme levels are governed by the rates of de novo enzyme synthesis and degradation.

Alice Ban Ke,1 Amin Rostami-Hodjegan,2,3 Ping Zhao,4 and Jashvant D. Unadkat5.

Model-informed precision dosing (MIPD) has become synonymous with modern approaches for individualizing drug therapy, in which the characteristics of each patient are considered as opposed to applying a one-size-fits-all alternative. This review provides a brief account of the current knowledge, pra …

Professor of Systems Pharmacology, University of Manchester, UK. Verified email at manchester.ac.uk - Homepage. Translational Modelling in Drug 2018-03-27 · Loop is the open research network that increases the discoverability and impact of researchers and their work. Loop enables you to stay up-to-date with the latest discoveries and news, connect with researchers and form new collaborations.

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This review provides a brief account of the current knowledge, practices, and opinions on MIPD while defining an achievable vision for MIPD in clinical care based 2012-12-13 · Background: Pregnancy is associated with considerable changes in the physiological, anatomical and biochemical attributes in women. These may alter the exposure to xenobiotics between pregnant and non-pregnant women who receive similar doses, with implications for different susceptibility to environmental pollutants or therapeutic agents. Title: Prediction of Intestinal First-Pass Drug Metabolism VOLUME: 8 ISSUE: 7 Author(s):Jiansong Yang, Masoud Jamei, Karen Rowland Yeo, Geoffrey T. Tucker and Amin Rostami-Hodjegan Amin Rostami-Hodjegan is the author of ADME (0.0 avg rating, 0 ratings, 0 reviews, published 2009) and Biosimulation in Biomedical Research, Health Care Semantic Scholar profile for A. Rostami-Hodjegan, with 139 highly influential citations and 78 scientific research papers. 2016-03-29 · Prediction of drug-drug interactions arising from CYP3A induction using a physiologically-based dynamic model Correspondence: A. Rostami‐Hodjegan (amin.rostami@manchester.ac.uk)Search for more papers by this author. Amin Rostami‐Hodjegan. Corresponding Author.

Skip slideshow. Most frequent co Amin Rostami-Hodjegan, Professor of Systems Pharmacology, University of Manchester Amin is a Professor of Systems Pharmacology at the Centre for Applied Pharmacokinetic Research (CAPKR) in the School of Pharmacy and Pharmaceutical Sciences at the University of Manchester. He has an active program of training PhD students in Research Explorer.
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He was the first full Professor appointed with the title of Systems Pharmacology.

Amin is the Director of the Centre for Applied Pharmacokinetic Research (CAPKR) at the University of Manchester.
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15 May 2017 in silico clinical trials of drug candidates. Amin Rostami-Hodjegan Amin. rostami@mancehster.ac.uk. An average 55 year-old patient receives

Jiansong Yang, Masoud Jamei, Karen Rowland Yeo, Geoffrey T. Tucker and Amin Rostami-Hodjegan, “ Prediction of Intestinal First-Pass Drug Metabolism”, Current Drug AAPS J. 2016 Sep;18(5):1082-94. doi: 10.1208/s12248-016-9959-1.

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Pris: 1769 kr. Häftad, 2014. Skickas inom 10-15 vardagar. Köp Biosimulation in Biomedical Research, Health Care and Drug Development av Erik Mosekilde, Olga Sosnovtseva, Amin Rostami-Hodjegan på Bokus.com.

Characterization of CYP2B6 K262R allelic variants by quantitative allele-specific proteomics using a QconCAT standard. Journal of Pharmaceutical and Biomedical Analysis 2020, 178 , 112901.

in biomedical research, health care and drug development / [ed] Erik Mosekilde, Olga Sosnovtseva, Amin Rostami-Hodjegan, Wien: Springer, 2012, s.

FAST BREAKING PAPERS - 2008 April 2008 Amin Rostami-Hodjegan talks with ScienceWatch.com and answers a few questions about this month's Fast Breaking Paper in the field of Pharmacology & Toxicology.

Amin Rostami-Hodjegan Physiologically-based pharmacokinetic (PBPK) models provide a framework for in vitro-in vivo extrapolation of metabolic drug clearance. Many of the concepts in PBPK can have Amin Rostami-Hodjegan The gut wall consists of many biological elements, including enterocytes. Rapid turnover, a prominent feature of the enterocytes, has generally been ignored in the development Amin Rostami-Hodjegan Hartmut Derendorf (2010 – 2020) Oliver von Richter (2010 – 2018) Address correspondence and reprint requests to Dr. Amin Rostami-Hodjegan, Molecular Pharmacology and Pharmacogenetics, Floor L, The Royal Hallamshire Hospital, Sheffield S10 2JF, UK. E-mail: a.rostami@sheffield.ac.uk. Rachel H. Rose1, Kevin Feng1, David B. Turner1, Amin Rostami-Hodjegan1,2, Masoud Jamei1 1. Simcyp Limited (a Certara Company), Sheffield, UK; 2. Manchester School of Pharmacy, University of Manchester, UK • Following a meal, physiological changes occur that can impact upon drug absorption and elimination. Jiansong Yang, Masoud Jamei, Karen Rowland Yeo, Geoffrey T. Tucker and Amin Rostami-Hodjegan, “ Prediction of Intestinal First-Pass Drug Metabolism”, Current Drug AAPS J. 2016 Sep;18(5):1082-94.